diff --git a/src/misc.cpp b/src/misc.cpp
--- a/src/misc.cpp
+++ b/src/misc.cpp
@@ -29,6 +29,7 @@
 #include "station_kdtree.h"
 #include "town_kdtree.h"
 #include "viewport_kdtree.h"
+#include "newgrf_profiling.h"
 
 #include "safeguards.h"
 
@@ -69,6 +70,8 @@ void InitializeGame(uint size_x, uint si
 	_thd.redsq = INVALID_TILE;
 	if (reset_settings) MakeNewgameSettingsLive();
 
+	_newgrf_profilers.clear();
+
 	if (reset_date) {
 		SetDate(ConvertYMDToDate(_settings_game.game_creation.starting_year, 0, 1), 0);
 		InitializeOldNames();