diff --git a/src/newgrf_industries.cpp b/src/newgrf_industries.cpp
--- a/src/newgrf_industries.cpp
+++ b/src/newgrf_industries.cpp
@@ -643,9 +643,11 @@ void IndustryProductionCallback(Industry
 		if (group->version < 2) {
 			/* Callback parameters map directly to industry cargo slot indices */
 			for (uint i = 0; i < group->num_input; i++) {
+				if (!IsValidCargoID(ind->accepted[i].cargo)) continue;
 				ind->accepted[i].waiting = ClampTo<uint16_t>(ind->accepted[i].waiting - DerefIndProd(group->subtract_input[i], deref) * multiplier);
 			}
 			for (uint i = 0; i < group->num_output; i++) {
+				if (!IsValidCargoID(ind->produced[i].cargo)) continue;
 				ind->produced[i].waiting = ClampTo<uint16_t>(ind->produced[i].waiting + std::max(DerefIndProd(group->add_output[i], deref), 0) * multiplier);
 			}
 		} else {